Occupation, Job Retention and Pseudoxanthoma Elasticum (PXE)
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Published on: June 14, 2021
Charlotte Regnault-Leuger1, Thomas David1, Hélène Humeau2
1Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Ester Team, SFR ICAT, F-49000 Angers, France.
Objective:
To assess the impact of pseudoxanthoma elasticum (PXE) on employment, and occupational support strategies.
Methods:
A cross-sectional study was conducted among working-age patients followed at the French PXE Center. Occupational status, disease-related impairments, workplace difficulties, and job retention strategies were assessed through a phone questionnaire.
Results:
Among 99 patients (43.8 ± 11.9 years), 9 reported job loss or company changes attributable to PXE. Decreased visual acuity was significantly associated with lower employment rates (p=0.018), workplace restrictions (p=0.050), mood disturbances (p=0.004), and reduced professional self-esteem (p=0.009). Patients with visual impairment were more likely to receive OP support (p<0.001), disabled worker status (p<0.001), or disability pensions (p=0.008).
Conclusions:
PXE can substantially affect occupational functioning, predominantly through visual impairment. Further studies are needed to evaluate the effectiveness of job retention strategies in patients with PXE.
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