Innovative therapies for IgE-mediated type I allergies

Against the background of increasing prevalence of IgE-mediated type I allergies, novel approaches for treatment are urgently needed. With treatment anchored in historical developments over a century, a new layer of improvements and next-generation approaches are about to enter the stage. Advances in understanding the cellular and molecular signatures of IgE-mediated diseases, and in particular molecular technologies have paved the way for new approaches aiming at improved diagnostics and more efficient treatment. In recent years, novel technologies have been established and applied in the development of approaches which might overcome current limitations and provide novel windows of opportunity. These approaches give a first glimpse of the future treatment possibilities in allergic diseases.