[Fosfomycin for treating neurological infections]
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Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
Published on: September 15, 2014
1Dept. of Neurosurgery, University Hospital Hradec Králové, Czech Republic;
Abstract:
Intravenous fosfomycin, an antibiotic known for decades, is increasingly being clinically used as a reserve component of combination antimicrobial therapy for a wide range of indications. Its pharmacokinetic properties and unique mechanism of action offer numerous advantages in treating the most severe central nervous system infections. Its importance is growing alongside the rising prevalence of infections - particularly nosocomial ones - caused by resistant bacteria. Intravenous fosfomycin offers a favorable safety profile and high efficacy within combination treatment regimens. Keywords: intravenous fosfomycin, CNS infections, meningitis, ventriculitis, antibiotic resistance, external ventricular drainage.
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