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Granulomatos cervical lymphadenitis.

K E Schroder, H H Elverland, I W Mair

    The Journal of Otolaryngology
    |April 1, 1979
    PubMed
    Summary
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    Granulomatous lymphadenitis affects nearly 21% of cervical lymph node cases. Atypical mycobacteria infection, though underrecognized, is a significant cause, with surgery recommended for treatment.

    Area of Science:

    • Pathology
    • Infectious Diseases
    • Microbiology

    Background:

    • Cervical lymphadenitis is a common clinical presentation.
    • Granulomatous inflammation is a key pathological finding in lymph nodes.
    • Various infectious agents and conditions can cause granulomatous lymphadenitis.

    Purpose of the Study:

    • To review the incidence and causes of granulomatous lymphadenitis in cervical lymph nodes.
    • To highlight the clinical features and diagnostic criteria for infection with atypical mycobacteria.
    • To recommend optimal treatment strategies for granulomatous lymphadenitis, particularly due to atypical mycobacteria.

    Main Methods:

    • Retrospective review of 139 cases with pathologically involved cervical lymph nodes.
    • Classification of granulomatous lymphadenitis based on etiology (sarcoidosis, tularemia, tuberculosis, atypical mycobacteria).

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  • Analysis of clinical features associated with atypical mycobacterial infections.

    • Main Results:

    • Granulomatous lymphadenitis was identified in 29 patients (20.9%).
    • Causes included sarcoidosis (2 cases), tularemia (10 cases), tuberculous lymphadenitis (5 cases), and atypical mycobacteria (12 cases).
    • Atypical mycobacterial infection represented 8.7% of cases and exhibited specific, though often unrecognized, clinical features.

    Conclusions:

    • Granulomatous lymphadenitis is a significant finding in cervical lymph node pathology.
    • Infection with atypical mycobacteria is an underrecognized cause of granulomatous lymphadenitis.
    • Surgical intervention is recommended as the primary treatment for atypical mycobacterial lymphadenitis.