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Rhinoviraemia.

G E Urquhart, E J Stott

    British Medical Journal
    |October 3, 1970
    PubMed
    Summary
    This summary is machine-generated.

    Human rhinoviruses were found in infant blood samples, suggesting rare instances of viremia. This rare occurrence is infrequently linked to rhinovirus infections or infant death.

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    Area of Science:

    • Virology
    • Pediatric Infectious Diseases
    • Molecular Biology

    Background:

    • Rhinoviruses are common respiratory pathogens in infants.
    • The presence of rhinoviruses in the bloodstream (viremia) is not well-documented.
    • Understanding viral dissemination is crucial for pediatric health.

    Purpose of the Study:

    • To investigate the occurrence of human rhinovirus viremia in infants.
    • To determine the association between rhinovirus detection in blood and respiratory samples.
    • To assess the significance of rhinovirus viremia in infant mortality.

    Main Methods:

    • Post-mortem serum samples from infants were analyzed for rhinovirus.
    • Viral isolation and potentially molecular detection methods were employed.

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  • Comparison of viral findings in serum versus respiratory tract samples.

    • Main Results:

    • Human rhinoviruses were successfully isolated from the serum of two deceased infants.
    • Rhinoviruses were not detected in the serum of ten other infants with respiratory viral infections.
    • This suggests that rhinovirus viremia is an infrequent event.

    Conclusions:

    • This study presents the first reported isolation of human rhinoviruses from infant blood.
    • True rhinovirus viremia appears to be rare, even in cases of rhinovirus infection.
    • The findings indicate that viremia is infrequently associated with clinical rhinovirus infections and mortality in infants.