A curve-fitting procedure for the study of the binding of small molecules to multi-subunit proteins

A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells.

Science (New York, N.Y.)·2001

Propagating conformational changes over long (and short) distances in proteins.

Proceedings of the National Academy of Sciences of the United States of America·2001

Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.

Biochemistry·2001

Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase.

Biochemistry·2000

Biosynthetic incorporation of unnatural sialic acids into polysialic acid on neural cells.

Glycobiology·2000

Sites of binding and orientation in a four-location model for protein stereospecificity.

IUBMB life·2000

[Spectral and thermal characterization of cephalosporins. I. Cefadroxil and cefalexin].

Il Farmaco; edizione scientifica·1988

Synthesis and antimicrobial activity of some pyrrole derivatives. III--2-(4-arylpiperazino)-3-ethoxycarbonyl-5-aryl-pyrrole derivatives.

Il Farmaco; edizione scientifica·1988

[Synthesis, antisecretory, and anti-ulcer activity of new 5-arylidene-2-ureidoalkyl-3-pyridazinones].

Il Farmaco; edizione scientifica·1988

3,5-Diphenyl-1H-pyrazole derivatives. II--N-substituted 1-(2-aminoethyl)-3,5-diphenyl-1H-pyrazoles and their 4-bromo derivatives with analgesic and other activities.

Il Farmaco; edizione scientifica·1988

How medicinal chemistry triggers fundamental research in heterocyclic chemistry. The chemistry of 4-hydroxy-2-pyrones and a new imidazole antifungal agent.

Il Farmaco; edizione scientifica·1988

S-Aryl(tetramethyl)isothiouronium salts as possible antimicrobial agents--III.

Il Farmaco; edizione scientifica·1988

Phase 1b ATMOS trial of the inhaled sGC activator mosliciguat in patients with PAH/CTEPH.

Thorax·2026

Dissecting affinity determinants of benzotriazine-based ligands at sigma-1 receptor: a multilevel molecular dynamics analysis.

Bioorganic chemistry·2026

Theoretical Study on the Photophysical Mechanism for the Detection of Biothiols Based on the 1,3,4-Thiadiazole Fluorescence Probe.

Journal of fluorescence·2026

Integrating DFT-assisted optimization into HPLC-DAD method development: simultaneous determination of four acylphosphine oxide compounds in nail gel polish.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026

5-Carboxamide-Substituted Barbituric Acids: Promising Scaffolds for Drug Development against Mycobacterium tuberculosis.

ACS infectious diseases·2026

Robots and Minimal, Physics-Informed Features: A Hybrid Framework for Enzyme Catalysis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

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A curve-fitting procedure for the study of the binding of small molecules to multi-subunit proteins

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A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells.

Propagating conformational changes over long (and short) distances in proteins.

Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.

Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase.

Biosynthetic incorporation of unnatural sialic acids into polysialic acid on neural cells.

Sites of binding and orientation in a four-location model for protein stereospecificity.

[Spectral and thermal characterization of cephalosporins. I. Cefadroxil and cefalexin].

Synthesis and antimicrobial activity of some pyrrole derivatives. III--2-(4-arylpiperazino)-3-ethoxycarbonyl-5-aryl-pyrrole derivatives.

[Synthesis, antisecretory, and anti-ulcer activity of new 5-arylidene-2-ureidoalkyl-3-pyridazinones].

3,5-Diphenyl-1H-pyrazole derivatives. II--N-substituted 1-(2-aminoethyl)-3,5-diphenyl-1H-pyrazoles and their 4-bromo derivatives with analgesic and other activities.

How medicinal chemistry triggers fundamental research in heterocyclic chemistry. The chemistry of 4-hydroxy-2-pyrones and a new imidazole antifungal agent.

S-Aryl(tetramethyl)isothiouronium salts as possible antimicrobial agents--III.

Phase 1b ATMOS trial of the inhaled sGC activator mosliciguat in patients with PAH/CTEPH.

Dissecting affinity determinants of benzotriazine-based ligands at sigma-1 receptor: a multilevel molecular dynamics analysis.

Theoretical Study on the Photophysical Mechanism for the Detection of Biothiols Based on the 1,3,4-Thiadiazole Fluorescence Probe.

Integrating DFT-assisted optimization into HPLC-DAD method development: simultaneous determination of four acylphosphine oxide compounds in nail gel polish.

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A curve-fitting procedure for the study of the binding of small molecules to multi-subunit proteins

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