[Defibrination treatment of progressive scleroderma]

The authors report about the defibrination therapy with the enzyme préparation Arwin in sclerodermia progressiva. From 16 patients with sclerodermia progressiva, 9 patients showed a clinically good result. Three patients showed a certain improvement, but objectively, the results are doubtful. Four of the patients did not react to the therapy clinically nor in the applied tests. We have tried to prove the effect of the enzyme preparation Arwin in patients with sclerodermia progressiva with venous occlusion plethysmography and by isotope Technetium 99 with the use of a Gamma-camera. The results will be reported.