Effect of urea on the divalent cation binding site of pyruvate kinase

Structures and mechanisms of Nudix hydrolases.

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Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy.

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Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies.

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The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

Biochemistry·2001

NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase.

Biochemistry·2000

GDP-mannose mannosyl hydrolase catalyzes nucleophilic substitution at carbon, unlike all other Nudix hydrolases.

Biochemistry·2000

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Enhanced SIRT3 activity potentiates germinal center epigenetic modulation through α-ketoglutarate.

The Journal of biological chemistry·2026

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The Journal of biological chemistry·2026

Genetic and biochemical screens identify MGAT1 as a druggable glycosyltransferase target in STK11-mutant lung cancer.

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The Journal of biological chemistry·2026

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The Journal of biological chemistry·2026

Orbital-selective X-ray solvatochromism in aqueous nitromethane resolved via a dipole-field interaction model.

Chemical communications (Cambridge, England)·2026

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Real-time in situ study of adsorption kinetics in PMMA thin films using infrared spectroscopy.

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Related Experiment Videos

Effect of urea on the divalent cation binding site of pyruvate kinase

Related Concept Videos

Structures and mechanisms of Nudix hydrolases.

Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy.

Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies.

The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase.

GDP-mannose mannosyl hydrolase catalyzes nucleophilic substitution at carbon, unlike all other Nudix hydrolases.

F-actin-dependent activation of NADPH oxidase 5 by the vacuolar-type ATPase.

Enhanced SIRT3 activity potentiates germinal center epigenetic modulation through α-ketoglutarate.

Mammalian DNA methyltransferases in DNA methylation and imprinted gene expression in extraembryonic ectoderm of post-implantation embryos.

Genetic and biochemical screens identify MGAT1 as a druggable glycosyltransferase target in STK11-mutant lung cancer.

GATA3-driven CDC20 activation facilitates tumor growth and metastasis through suppressing Bax/Bcl-2 ratio and boosting EMT process in neuroblastoma.

5-Iodotubercidin inhibits Epithelial to Mesenchymal Transition by inhibiting IKK/NFκB-dependent gene expression.

Orbital-selective X-ray solvatochromism in aqueous nitromethane resolved via a dipole-field interaction model.

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Effect of urea on the divalent cation binding site of pyruvate kinase

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