[Hemostasis system in lung cancer, benign tumors and chronic nonspecific pneumonias]

A comparative study, condicted on the coagulation status, indicated that tumor and chronic inflammatory processes in the lung as associated with high blood content of fibrinogen and fibrinogen B, the increased plasma tolerance to heparin and degree of thrombotest with a compensatory increase of the heparin content and antithrombin activity. Lung tumor patients contrary to patients with pneumonias showed a high thromboplastin activity and reduced fibrinolysis indices. The activation of euglobulin fibrinolysis is characteristic of the hemostasis system in patients with chronic pneumonias. The revealed alterations may be used both for timely prophylaxis of coagulopathy and as an adjuvant method in the differential diagnosis.