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Radiologic heart volume and subsequent mortality.

D Christie, A Gardner

    Acta Radiologica: Diagnosis
    |January 1, 1979
    PubMed
    Summary
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    Radiologic heart volume, measured from chest X-rays, predicts cardiovascular disease mortality in men over 40. Higher heart volume indicates increased risk for both short-term and long-term death.

    Area of Science:

    • Cardiology
    • Radiology
    • Public Health

    Background:

    • Cardiovascular disease remains a leading cause of mortality worldwide.
    • Accurate risk stratification tools are crucial for early intervention and prevention strategies.
    • The prognostic value of radiologic heart volume in predicting long-term mortality requires further investigation.

    Purpose of the Study:

    • To investigate the association between radiologic heart volume and all-cause and cardiovascular disease mortality.
    • To determine if radiologic heart volume is an independent predictor of mortality over different time intervals.

    Main Methods:

    • A cohort of 12,630 men aged 40 and above from the London Civil Service Health Survey were included.
    • Radiologic heart volume was calculated from chest X-rays (p.a. and lateral views).

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  • Mortality data was analyzed for subjects with calculable heart volume (n=1,390) over short-term (within 5 years) and long-term (beyond 5 years) follow-up periods.

    • Main Results:

    • A stepwise increase in mortality was observed with increasing quintiles of heart volume for deaths within the first 5 years.
    • Radiologic heart volume was found to predict death from cardiovascular disease within 5 years of examination.
    • The predictive value of radiologic heart volume extended to deaths occurring more than 5 years after the initial examination.

    Conclusions:

    • Radiologic heart volume is a significant predictor of cardiovascular disease mortality in middle-aged and older men.
    • Increased heart volume identified through chest radiography is associated with elevated risk of both short-term and long-term mortality.
    • Radiologic heart volume can serve as a valuable, non-invasive biomarker for cardiovascular risk assessment.