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Group D streptococcal septicemia in the neonate
American Journal of Diseases of Children (1960)
|May 1, 1979
Summary
Group D Streptococcus can cause severe neonatal septicemia, leading to infant death and hydrocephalus. Ampicillin sodium with kanamycin or gentamicin sulfate is recommended for treating neonatal infections caused by this pathogen.
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Microbiology
Background:
- Neonatal septicemia poses a significant threat to infant health.
- Group D Streptococcus, including enterococci and nonenterococci, are increasingly recognized as potential neonatal pathogens.
Purpose of the Study:
- To review the clinical course of neonatal septicemia caused by Group D Streptococcus.
- To identify optimal antibiotic treatments for this condition in newborns.
Main Methods:
- Retrospective review of 11 neonatal patients diagnosed with Group D streptococcal septicemia.
- Analysis of clinical outcomes, including mortality and complications.
- Evaluation of antibiotic efficacy.
Main Results:
- Two of the 11 infants (18.2%) died from septicemia.
- One infant developed hydrocephalus as a complication.
- Ampicillin sodium in combination with kanamycin sulfate or gentamicin sulfate demonstrated effectiveness.
Conclusions:
- Group D Streptococcus should be considered a significant pathogen in neonatal infections.
- Prompt and appropriate antibiotic therapy is crucial for improving outcomes.
- Ampicillin sodium plus kanamycin or gentamicin sulfate are the recommended antibiotics for neonatal Group D streptococcal septicemia.