Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Model for vesicular stomatitis virus.

B Cartwright, C J Smale, F Brown

    Journal of Virology
    |August 1, 1972
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Positive Neutrino Masses with DESI DR2 via Matter Conversion to Dark Energy.

    Physical review letters·2025
    Same author

    Anticoagulation for cardiopulmonary bypass, Part 2: alternatives and pathological states.

    BJA education·2023
    Same author

    Anticoagulation for cardiopulmonary bypass: part one.

    BJA education·2023
    Same author

    Is this the end of the Oral and Maxillofacial Toolbox? A retrospective analysis of funding for acute OMFS soft tissue trauma provision within the UK.

    The British journal of oral & maxillofacial surgery·2020
    Same author

    Retrieval of critically ill adults using extracorporeal membrane oxygenation: the nine-year experience in New South Wales.

    Anaesthesia and intensive care·2018
    Same author

    ESHRE Guideline: management of women with premature ovarian insufficiency.

    Human reproduction (Oxford, England)·2016
    Same journal

    Something old, something new? Herpesvirus genome packaging examined in light of lessons from the tailed bacteriophages.

    Journal of virology·2026
    Same journal

    Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells.

    Journal of virology·2026
    Same journal

    Live human metapneumovirus vaccine candidates attenuated by temperature sensitivity mutations from human respiratory syncytial virus.

    Journal of virology·2026
    Same journal

    Structure and functional analyses of vaccinia virus J5 protein reveal distinct determinants for entry-fusion complex assembly and activation.

    Journal of virology·2026
    Same journal

    Coronavirus membrane protein with a fluorescent protein tag enables particle tracking for the study of virus assembly and egress in live cells.

    Journal of virology·2026
    Same journal

    Disruption of the S1/S2 multibasic cleavage site attenuates infectious bronchitis virus, while S2' partially restores viral virulence and expands tissue tropism.

    Journal of virology·2026
    See all related articles

    Vesicular stomatitis virus (VSV) has single-stranded RNA and three main proteins. Calculations reveal VSV has about 500 surface projections, 1,100 ribonucleoprotein units, and 1,600 matrix protein units.

    Area of Science:

    • Virology
    • Molecular Biology
    • Structural Biology

    Background:

    • Vesicular stomatitis virus (VSV) is a significant model virus for studying RNA virus structure and replication.
    • Understanding the precise composition and structure of VSV is crucial for developing antiviral strategies and vaccines.

    Purpose of the Study:

    • To determine the molecular weight and subunit composition of Vesicular Stomatitis Virus.
    • To quantify the number of protein units comprising the virus's structural components.
    • To propose models for the structural organization of VSV based on its protein composition.

    Main Methods:

    • Molecular weight determination of viral RNA and proteins.
    • Estimation of the proportion of individual viral proteins.
    • Calculation of the number of protein subunits per viral structure.

    Related Experiment Videos

    Main Results:

    • VSV contains single-stranded RNA (3.6 x 10^6 Da) and three major proteins (75 x 10^3, 57 x 10^3, and 32.5 x 10^3 Da).
    • These proteins correspond to surface projections, ribonucleoprotein, and matrix protein, respectively.
    • Calculations indicate approximately 500 surface projections, 1,100 ribonucleoprotein units, and 1,600 matrix protein units per virion.

    Conclusions:

    • The study elucidates the quantitative protein composition of Vesicular Stomatitis Virus.
    • The findings provide a basis for understanding the structural organization and assembly of VSV.
    • Proposed models highlight the interrelationship of viral proteins in VSV structure.