Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

St. Louis encephalitis: the Chicago experience.

R M Zweighaft, C Rasmussen, O Brolnitsky

    The American Journal of Tropical Medicine and Hygiene
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Incident rheumatoid arthritis in patients living in Turkey and in Denmark: a comparative clinical, genetic, and serological study.

    Scandinavian journal of rheumatology·2024
    Same author

    Antibody response in patients with autoimmune inflammatory rheumatic disease after pneumococcal polysaccharide prime vaccination or revaccination.

    Scandinavian journal of rheumatology·2022
    Same author

    Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2021
    Same author

    Soil organic carbon is not just for soil scientists: measurement recommendations for diverse practitioners.

    Ecological applications : a publication of the Ecological Society of America·2021
    Same author

    A New Species of Tetragona Lepeletier & Serville, 1828 from the "truncata group" and New Distribution Records of T. truncata Moure, 1971 (Hymenoptera: Apidae).

    Neotropical entomology·2020
    Same author

    COVID-19 and Involvement of the Corpus Callosum: Potential Effect of the Cytokine Storm?

    AJNR. American journal of neuroradiology·2020
    Same journal

    Long-Term Mortality among Hospitalized Adults with Sepsis in Uganda: A Prospective Cohort Study.

    The American journal of tropical medicine and hygiene·2026
    Same journal

    Arbovirus Circulation among Patients with Acute Encephalitis: West Nile Virus Infection among Humans in Bangladesh, 2022.

    The American journal of tropical medicine and hygiene·2026
    Same journal

    Vitamin D Deficiency and Severe Dengue Fever: A Systematic Review and Meta-Analysis.

    The American journal of tropical medicine and hygiene·2026
    Same journal

    The Weather-Child Morbidity Link and the Modifying Effect of Maternal Education and Sanitation: Evidence from Sub-Saharan Africa.

    The American journal of tropical medicine and hygiene·2026
    Same journal

    Use of a Gamification Platform to Teach Tropical Medicine: A Pilot Study.

    The American journal of tropical medicine and hygiene·2026
    Same journal

    The Proposed United States Office of Management and Budget Rule for Managing Biomedical Research Grants and Cooperative Agreements Needs to Change.

    The American journal of tropical medicine and hygiene·2026
    See all related articles

    The 1975 Chicago outbreak was the largest documented St. Louis encephalitis (SLE) epidemic in the US. It disproportionately affected older individuals, with cases clustering in southwestern suburbs.

    Area of Science:

    • Epidemiology
    • Public Health
    • Infectious Diseases

    Background:

    • The 1975 Chicago outbreak represented the largest laboratory-documented St. Louis encephalitis (SLE) epidemic in the United States.
    • St. Louis encephalitis had not been previously documented in the Chicago area before this event.

    Purpose of the Study:

    • To document and analyze the characteristics of the 1975 St. Louis encephalitis outbreak in the Chicago metropolitan area.
    • To understand the epidemiology, including geographical distribution, age-specific attack rates, and mortality associated with the SLE outbreak.

    Main Methods:

    • Investigation of 1,456 reported illnesses within a six-county Chicago area.
    • Classification of cases into confirmed/probable SLE and suspected SLE.
    • Geographical mapping of case clusters and analysis of demographic data, including age and sex.

    Related Experiment Videos

    Main Results:

    • 326 confirmed or probable SLE cases and 420 suspected cases were identified.
    • The outbreak peaked in early September and continued through October, with cases geographically clustered in southwestern suburbs.
    • A direct correlation was observed between increasing age and higher attack rates, illness severity, and mortality. Males and females were equally affected, with 36 deaths.

    Conclusions:

    • The 1975 epidemic was a significant public health event, marking the first documented occurrence of St. Louis encephalitis in the Chicago area.
    • Age was a critical factor influencing the severity and outcome of SLE during this outbreak.
    • Geographical clustering suggests localized transmission dynamics that warrant further investigation.