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A method for sampling halothane and enflurane present in trace amounts in ambient air.

A G Burm, J Spierdijk

    Anesthesiology
    |March 1, 1979
    PubMed
    Summary

    A new method effectively samples halothane and enflurane in ambient air using Porapak Q tubes and gas chromatography. This technique allows for accurate measurement of anesthetic agents for personal or environmental monitoring.

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    Area of Science:

    • Environmental Chemistry
    • Occupational Health
    • Analytical Chemistry

    Background:

    • Halothane and enflurane are common anesthetic agents.
    • Accurate monitoring of anesthetic agent concentrations in ambient air is crucial for occupational safety and environmental assessment.

    Purpose of the Study:

    • To describe a novel method for sampling and quantifying halothane and enflurane in ambient air.
    • To provide a versatile sampling technique suitable for both short-term and long-term exposure assessments.

    Main Methods:

    • Air sampling using a tube packed with Porapak Q adsorbent to capture anesthetic agents.
    • Thermal desorption of captured agents from the sampling tube.
    • Quantitative analysis of anesthetic agents via gas chromatography.

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    Main Results:

    • The described method allows for the effective absorption of halothane and enflurane by Porapak Q.
    • Gas chromatography after thermal desorption provides accurate determination of absorbed anesthetic agent amounts.
    • The method is adaptable for 'spot' sampling, personal monitoring, and determining mean whole-room concentrations over extended periods.

    Conclusions:

    • A reliable and adaptable method for sampling halothane and enflurane in ambient air has been developed.
    • This technique facilitates precise assessment of occupational exposure and environmental concentrations of these anesthetic agents.