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Updated: Jul 29, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Abstract:
Although not uncommon, and certainly not rare, frontal sinus mucocele was seen in 4 cases by the authors. Since one of the cases was rather unusual, we were prompted to evaluate the subject and prepare this manuscript. Gradual onset of unilateral proptosis should make one suspicious of a mucocele involving the paranasal sinuses, the frontal and ethmoid being the 2 most common locations. Diplopia, due to limited ocular motility on upward gaze, along with proptosis and epiphora are frequently the presenting symptoms which, in one particular case, paradoxically improved at first with topical anti-inflammatory therapy . A team approach (ophthalmologist, radiologist, otorhinolaryngologist, and neurosurgeon) are essential for an accurate diagnosis and therapeutic approach to this problem. The use of a precut template from the Caldwell projection is a very useful device to outline the contours of the frontal sinus during surgery. The not-so-frequent use of abdominal fat to fill the frontal sinus cavity is presented with no apparent postoperative fat necrosis. A 5-year follow-up has shown the patient to be free of recurrences.
Insights
Frontal sinus mucoceles can cause unilateral proptosis and diplopia. Multidisciplinary teams and surgical techniques, including abdominal fat grafting, offer effective treatment with no recurrence in a 5-year follow-up.
Area of Science:
- Otolaryngology
- Ophthalmology
- Neurosurgery
Background:
- Frontal sinus mucoceles, though not rare, present diagnostic and therapeutic challenges.
- Unilateral proptosis and diplopia are key indicators of paranasal sinus mucoceles, commonly affecting frontal and ethmoid sinuses.
Observation:
- Four cases of frontal sinus mucocele were analyzed, with one unusual presentation.
- Symptoms included gradual unilateral proptosis, diplopia due to limited upward ocular motility, and epiphora.
- One case showed paradoxical initial improvement with topical anti-inflammatory therapy.
Findings:
- A multidisciplinary team approach involving ophthalmologists, radiologists, otorhinolaryngologists, and neurosurgeons is crucial for accurate diagnosis and treatment.
- Surgical planning benefits from using a precut template from the Caldwell projection to delineate frontal sinus contours.
- Abdominal fat grafting for frontal sinus cavity obliteration was successfully employed without postoperative fat necrosis.
Implications:
- This study highlights the importance of considering frontal sinus mucoceles in cases of unilateral proptosis.
- Effective management requires a collaborative team approach and tailored surgical techniques.
- Long-term follow-up (5 years) demonstrated successful outcomes with no recurrence, validating the presented therapeutic strategy.
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