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SV40 virus transformation of mouse 3T3 cells does not specifically enhance sugar transport
Science (New York, N.Y.)
|March 23, 1973
Abstract:
The apparent enhancement of 2-deoxy-D-glucose uptake by mouse 3T3 cells accompanying transformation by SV40 virus is not due primarily to an effect on the transport process but to enhanced phosphorylation of the sugar by intracellular kinases. Moreover, the effect is not specifically a function of the presence of the viral genome, but is a reflection of the overall growth rate and physiological state of the cell.