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Leptomeningeal carcinomatosis with normal CSF features
Archives of Internal Medicine
|February 1, 1979
Summary
Leptomeningeal carcinomatosis can be diagnosed by cerebrospinal fluid (CSF) cytology even with normal CSF measurements. This diagnostic approach significantly altered patient treatment in two unusual cases.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Leptomeningeal carcinomatosis (LC) presents diagnostic challenges.
- Cerebrospinal fluid (CSF) analysis is crucial for diagnosing central nervous system (CNS) involvement.
- Typical CSF findings in LC include abnormal cell counts and protein levels.