Intravenous antibiotic therapy at home

Area of Science:

• Infectious Diseases
• Pharmacology
• Health Economics

Background:

• Hospitalization for intensive intravenous (IV) antibiotic therapy is common for serious infections.
• Many patients receiving IV antibiotics are not significantly disabled and can be managed outside the hospital.
• Serious infections like osteomyelitis and infective endocarditis often require prolonged IV antibiotic courses.

Purpose of the Study:

• To evaluate the feasibility and benefits of home-based IV antibiotic therapy for select patients.
• To assess the safety, efficacy, and economic impact of transitioning patients from hospital to home IV antibiotic treatment.
• To determine patient comfort and functional outcomes associated with home IV antibiotic administration.

Main Methods:

• Patients with osteomyelitis or infective endocarditis were selected for home IV antibiotic therapy.
• An specialized IV nurse team provided patient training for self-administration of antibiotics.
• Patients underwent regular clinic visits for IV catheter maintenance and antibiotic supply replenishment every 48 hours.

Main Results:

• Home-based IV antibiotic therapy was safely administered to patients.
• Significant cost savings were achieved, with at least $1,600 saved per patient course.
• Patients reported increased comfort at home, with some returning to work or school.

Conclusions:

• Home IV antibiotic therapy is a safe and effective alternative for stable patients with serious infections.
• This model of care offers substantial financial benefits and improves patient quality of life.
• Transitioning to home-based IV antibiotic treatment facilitates faster recovery and return to normal activities.