Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new method for measuring PCO2 during anaesthesia.

D Z Frankel, G Sandham, A S Rebuck

    British Journal of Anaesthesia
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Bronchoalveolar lavage.

    Canadian Medical Association journal·2010
    Same author

    Protein purification with vapor-phase carbon dioxide.

    Biotechnology and bioengineering·1999
    Same author

    Is the short-term response to inhaled beta-adrenergic agonist sensitive or specific for distinguishing between asthma and COPD?

    Chest·1994
    Same author

    Assessment of airway tone in asthma. Comparison between double lung transplant patients and healthy subjects.

    The American review of respiratory disease·1993
    Same author

    Tracheobronchial dilation during isocapnic hypoxia in conscious humans.

    Journal of applied physiology (Bethesda, Md. : 1985)·1993
    Same author

    Trends in asthma and chronic obstructive pulmonary disease therapy in Canada, 1985 to 1990.

    The Journal of allergy and clinical immunology·1993
    Same journal

    Audit of procedural sedation complications using a novel digital application.

    British journal of anaesthesia·2026
    Same journal

    Social deprivation and morbidity and mortality after surgery. Comment on Br J Anaesth 2025; 135: 1193-1202.

    British journal of anaesthesia·2026
    Same journal

    Single-dose intraoperative methadone and QTc interval: a prospective observational cohort investigation.

    British journal of anaesthesia·2026
    Same journal

    Postoperative outcomes in older patients with postoperative delirium in the UK: timing of postoperative delirium screening in the SNAP-3 study. Comment on Br J Anaesth 2026; 136: 1578-87.

    British journal of anaesthesia·2026
    Same journal

    Population pharmacokinetic-pharmacodynamic analysis and dose optimisation of ciprofol in paediatric anaesthesia.

    British journal of anaesthesia·2026
    Same journal

    Global environmental and geo-economic impact of conservative versus liberal oxygen strategies in mechanically ventilated critically ill adults: an ecological country-level analysis.

    British journal of anaesthesia·2026
    See all related articles

    A novel method accurately estimates oxygenated mixed venous PCO2 (PVCO2) during general anesthesia. This technique allows for reliable estimation of arterial PCO2 (PaCO2) using expired gas analysis.

    Area of Science:

    • Anesthesiology
    • Respiratory Physiology
    • Medical Device Technology

    Background:

    • Accurate monitoring of mixed venous PCO2 (PVCO2) is crucial for assessing tissue perfusion and metabolic status during general anesthesia.
    • Current methods for PVCO2 measurement can be invasive or technically challenging in clinical settings.

    Purpose of the Study:

    • To evaluate a new, non-invasive method for estimating oxygenated mixed venous PCO2 (PVCO2) in patients under general anesthesia.
    • To determine the accuracy of this novel PVCO2 measurement technique by comparing it with simultaneously measured arterial PCO2 (PaCO2).

    Main Methods:

    • The method involves inflating lungs with varying carbon dioxide concentrations (0% and 12%) and analyzing expired gas before and after a breath-hold.
    • PVCO2 is calculated based on the difference in expired carbon dioxide concentrations.

    Related Experiment Videos

  • Simultaneous arterial PCO2 (PaCO2) measurements were obtained via radial artery puncture.

    • Main Results:

    • The study investigated a PaCO2 range of 3.2–6.13 kPa.
    • A strong correlation was observed between estimated PVCO2 and measured PaCO2, with the relationship described by PaCO2 = 0.87 PVCO2 – 0.44 (r = 0.91).

    Conclusions:

    • The evaluated method provides a reliable and accurate estimation of PVCO2 during general anesthesia.
    • This technique offers a valuable non-invasive approach for monitoring PCO2 levels, potentially improving patient management and safety.