Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renshaw cell activity in man.

J L Veale, S Rees

    Journal of Neurology, Neurosurgery, and Psychiatry
    |August 1, 1973
    PubMed
    Summary
    This summary is machine-generated.

    Investigating the H-reflex in triceps surae, this study found that both motor and sensory conditioning stimuli influence it. These conditioning effects are largely mediated by Renshaw cells, impacting motor neuron excitability.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reuse of a living donor kidney: A case study.

    Human immunology·2026
    Same author

    Recruitment and retention of participants in UK surgical trials: survey of key issues reported by trial staff.

    BJS open·2020
    Same author

    Using consensus methods to develop a Social Prescribing Learning Needs Framework for practitioners in Wales.

    Perspectives in public health·2020
    Same author

    Feasibility of measuring psychological resilience in hospitalized patients with acute illness: The Resilience After the Trauma of Acute Illness (RAFT) study.

    Acute medicine·2019
    Same author

    Doctors' decisions when disclosing their mental ill-health.

    Occupational medicine (Oxford, England)·2019
    Same author

    Living with vulval lichen sclerosus: a systematic review.

    The British journal of dermatology·2019
    Same journal

    Cancer risk and mortality in patients with multiple sclerosis in Finland: a retrospective population-based cohort study.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Characteristics and outcomes in electric scooter-related traumatic brain injuries in Helsinki.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Chronological ageing and ovarian reserve in MS: insights from anti-Müllerian hormone and disability progression.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Durable fluoropolymer drug-eluting stent versus bare-metal stent for the prevention of intracranial in-stent restenosis.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Correction: <i>How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?</i>

    Journal of neurology, neurosurgery, and psychiatry·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Motor Control
    • Human Physiology

    Background:

    • The H-reflex, an electrophysiological measure of spinal reflex excitability, is crucial for understanding motor control.
    • Previous research suggests complex interactions modulate the H-reflex, but the precise mechanisms of conditioning stimuli remain under investigation.

    Purpose of the Study:

    • To differentiate the effects of motor versus sensory conditioning stimuli on the H-reflex in the triceps surae.
    • To elucidate the role of Renshaw cells in mediating these conditioning effects on alpha motoneurons.

    Main Methods:

    • Percutaneous stimulation of the posterior tibial nerve to elicit the H-reflex in triceps surae.
    • Utilizing differential fiber sensitivity to stimulus pulse duration for selective motor or sensory conditioning.

    Related Experiment Videos

  • Analyzing H-reflex modulation (inhibition and facilitation) at various conditioning-test intervals.

    • Main Results:

    • Both motor and sensory conditioning produced an initial inhibition of the H-reflex (2-3 ms), followed by facilitation.
    • Peak facilitation occurred at 5-8 ms for motor conditioning and 6-10 ms for sensory conditioning.
    • A subsequent phase of inhibition followed the facilitation period for both conditioning types.

    Conclusions:

    • Motor conditioning effects on the H-reflex are attributed to Renshaw cell activation by antidromic volleys in motor axons.
    • Sensory conditioning effects, under the experimental conditions, are primarily mediated by Renshaw cell activation secondary to alpha motoneuron discharge.