Enhanced urinary excretion of 7,8-dihydro-6-hydroxylumazine by mice bearing the Ehrlich ascites tumour

A fluorescent urinary metabolite, excreted by mice carrying the Ehrlich ascites tumour (EAT), has been identified as 7,8-dihydro-6-hydroxylumazine. This finding agrees with other data which show that a disorder in pteridine metabolism is commonly associated with the presence of malignant growth.