Related Experiment Videos
Imidazole derivatives as inhibitors of cyclic nucleotide phosphodiesterases
Journal of Medicinal Chemistry
|November 1, 1974
Abstract
No abstract available in PubMed .
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Helping patients manage cancer-related fatigue.
Home healthcare nurse·2002
Serine and alanine mutagenesis of the nine native cysteine residues of the human A(1) adenosine receptor.
Biochemical pharmacology·2000
A photoaffinity probe covalently modifies the catalytic site of the cGMP-binding cGMP-specific phosphodiesterase (PDE-5).
Cell biochemistry and biophysics·1998
Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.
Journal of medicinal chemistry·2026
A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.
Journal of medicinal chemistry·2026
From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.
Journal of medicinal chemistry·2026
Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.
Journal of medicinal chemistry·2026
Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.
Journal of medicinal chemistry·2026
Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.
Journal of medicinal chemistry·2026