Thiamin turnover rate in some areas of rat brain and liver: a preliminary note

Thiamin turnover rates in some nervous structures and liver of rats were evaluated in a steady state condition, using thiamin- 14C as a tracer. The radioactivity contents were analyzed by means of a mamillary type compartmental model. Excluding the liver, turnover rate values of the nervous structures were ordered in the following sequence: sciatic nerve (0.58 microgram/g . h) less than cerebellum less than hypothalamus less than midbrain less than corpus striatum less than cerebral cortex (0.16 microgram/g . h).