Metabolism of cyclic adenosine 3':5'-monophosphate in somatic cell hybrids

To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...