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Related Experiment Videos

[Echocardiographic evaluation of left ventricular function in man].

E Most

    Fortschritte Der Medizin
    |April 12, 1979
    PubMed
    Summary

    Echocardiography accurately assesses left ventricular performance. Key indices like VCF max are sensitive to changes in heart rate, afterload, and inotropic state, proving valuable in clinical settings.

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    Area of Science:

    • Cardiology
    • Echocardiography
    • Physiology

    Context:

    • Echocardiography is a widely used non-invasive imaging technique for assessing cardiac function.
    • Understanding the influence of various physiological factors on echocardiographic indices is crucial for accurate interpretation.
    • Left ventricular performance evaluation is vital for diagnosing and managing cardiovascular diseases.

    Purpose:

    • To determine the impact of heart rate, afterload, inotropic state, and diastolic cycle length on echocardiographic ejection phase indices.
    • To evaluate the sensitivity of different left ventricular function indices to acute physiological changes in humans.
    • To assess the correlation between ejection phase indices and diastolic cycle length following premature beats and in atrial fibrillation.

    Summary:

    • Mean and maximal velocity of circumferential fiber shortening (VCF mean, VCF max) slightly increased with rapid atrial pacing.
    • Fractional shortening (FS%) and delta-VCF remained unaffected by acute heart rate variations.
    • VCF max and delta-VCF demonstrated high sensitivity to left ventricular function during Dobutamine infusion.
    • A linear correlation was observed between ejection phase indices and diastolic cycle length in premature beats and atrial fibrillation.

    Impact:

    • Echocardiographic assessment of left ventricular performance is clinically reliable.
    • Specific indices like VCF max are sensitive indicators of myocardial contractility changes.
    • Findings aid in the accurate interpretation of echocardiograms under various physiological conditions.

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