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[Tolerance of the polyvalent adsorbed influenza vaccine Alorbat]
A good local and systemic tolerance of the influenza virus vaccine Alorbat was observed after a single administration in 469 patients or after a second administration within 4--6 weeks in 132 patients. An improved manufacturing process led to a higher purity of the vaccine (less protein) and therefore to a diminuation of systemic reactions. In most cases, the local reactions observed cannot be attributed to a local irritation by the vaccine but rather to mechanical damage to the skin and subcutaneous tissue after injection with a jet injector. None of the side-effects necessitated medical treatment as the systemic reactions regressed within a few hours and the local reactions disappeared spontaneously within a few days.
A good local and systemic tolerance of the influenza virus vaccine Alorbat was observed after a single administration in 469 patients or after a second administration within 4--6 weeks in 132 patients. An improved manufacturing process led to a higher purity of the vaccine (less protein) and therefore to a diminuation of systemic reactions. In most cases, the local reactions observed cannot be attributed to a local irritation by the vaccine but rather to mechanical damage to the skin and subcutaneous tissue after injection with a jet injector. None of the side-effects necessitated medical treatment as the systemic reactions regressed within a few hours and the local reactions disappeared spontaneously within a few days.