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Phycomycosis in fifteen dogs and two cats
Abstract:
Phycomycosis was confirmed by histologic examination of biopsy specimens from 15 dogs and at necropsy in 2 cats. The fungal infections occurred most frequently in young adult dogs (1-3 yr) of the larger breeds. The gastrointestinal tract was the organ most commonly involved. Treatment by surgical excision, amphotericin B, and sodium iodide alone or in combination was attempted in five cases. Mortality was 100%.
Insights
Phycomycosis fungal infections were confirmed in 17 animals, primarily affecting young, large-breed dogs. Despite aggressive treatment, all affected animals experienced 100% mortality.
Area of Science:
- Veterinary Mycology
- Comparative Pathology
Background:
- Phycomycosis is a serious fungal infection affecting animals.
- Limited data exists on phycomycosis in domestic animals, particularly dogs and cats.
Purpose of the Study:
- To report the clinical and pathological findings of phycomycosis in dogs and cats.
- To evaluate treatment outcomes for this challenging fungal infection.
Main Methods:
- Histologic examination of biopsy and necropsy specimens.
- Clinical case observation and treatment monitoring.
Main Results:
- Phycomycosis confirmed in 15 dogs and 2 cats via histology.
- Infections predominantly occurred in young adult (1-3 years) large-breed dogs.
- The gastrointestinal tract was the most frequently involved organ system.
- Five cases underwent treatment including surgical excision, amphotericin B, and sodium iodide.
Conclusions:
- Phycomycosis presents a significant diagnostic challenge in veterinary medicine.
- Current treatment strategies for canine and feline phycomycosis appear ineffective, with a 100% mortality rate observed in this study.