Role of catheter surface morphology on intravascular thrombosis of plastic catheters

The role of catheter surface roughness in initiation and propagation of intravascular catheter thrombosis was studied in dogs, utilizing the scanning electron microscope. Catheters were inserted in major arteries and veins for 200 min and the animals then sacrificed. Catheter segments, both with and without associated thrombi, were scrutinized with the scanning electron microscope. No correlation was found between catheter surface roughness and thrombus formation, suggesting that the inherent chemical characteristics of the catheter is most important in the initiation of intravascular catheter thrombus formation.