Systemic Herpesvirus hominis in pregnancy.

Area of Science:

• Obstetrics and Gynecology
• Infectious Diseases
• Virology

Background:

• Primary genital herpesvirus (HSV) infection during pregnancy poses risks.
• Late gestation infections may facilitate systemic viral entry.

Observation:

• This report details a case of lethal disseminated herpetic infection.
• The infection followed a primary genital lesion in late gestation.

Findings:

• Pathologic findings reveal systemic spread of the herpesvirus.
• Pregnancy-induced physiological changes may compromise immune defenses against HSV.

Implications:

• Understanding pregnancy's impact on immune function is crucial for managing maternal HSV infections.
• Early detection and management of genital herpes in pregnant individuals are vital to prevent disseminated disease.