[Renin activity and functional status of the adrenal cortex in surgical intervention during ketamine anesthesia]

The renin activity and gluco- and mineralocorticoid adrenalocortical function were studied in 22 patients operated mainly on abdominal organs under the conditions of ketamine anesthesia. As noted, the ketamine injection followed with hypertension and tachicardia does not give rise to the renin activity and to the 11-OKS and aldosterone blood levels, as well. An evident trend to the increase of the concentration of the adrenocortical hormones, together with the occurrence of hypokemia and progressive hyperglycemia have been traced throughout the anesthesia and operation.