Related Experiment Video
Updated: Aug 27, 2026

The Tail Suspension Test
Published on: January 28, 2012
Lithium plus reserpine in refractory manic patients
Abstract:
The authors report on six refractory manic or schizo-affective manic male outpatients who failed to respond to lithium combined with a neuroleptic. A beneficial response was noted in most patients when reserpine was substituted for their currently prescribed standard neuroleptic; in some cases lithium dosage could then be reduced. No major side effects were encountered. The use of reserpine may offer an alternative mode of therapy for manic patients who cannot tolerate large doses of lithium or do not completely respond to lithium either alone or in combination with a standard neuroleptic.
Related Concept Videos
Psychosis and Antipsychotic Drugs: Overview
Psychosis: Goals of Pharmacotherapy
Mania and Antimanic Drugs: Overview
Antidepressant Drugs: MAOIs and Other Agents
Drug Therapy
Antianxiety Medications
Electroconvulsive Therapy

