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Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450.

Chemistry & biology·1996

Potency and selectivity of inhibition of human immunodeficiency virus protease by a small nonpeptide cyclic urea, DMP 323.

Antimicrobial agents and chemotherapy·1994

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors.

Science (New York, N.Y.)·1994

Evidence for specific N-terminal galanin fragment binding sites in the rat brain.

European journal of pharmacology·1992

Lycorine alleviates intrahepatic cholestasis by regulating bile acid metabolism via TKT/ATF3/BSEP pathway.

European journal of pharmacology·2026

European Journal of Pharmacology Neuropharmacological and behavioral characterization of 3F-phenetrazine, a novel amphetamine-like substance, in male mice and rats.

European journal of pharmacology·2026

Aucubin as a multifunctional iridoid glycoside: Molecular pharmacology and therapeutic mechanisms supporting its potential as a drug discovery scaffold.

European journal of pharmacology·2026

Attenuated Salmonella typhimurium VNP20009 L-forms suppress tumor growth and metastasis by inhibiting TGF-β1/Snail/Vimentin pathway in murine lung cancer.

European journal of pharmacology·2026

Sodium butyrate alleviates neuronal ferroptosis after gas explosion-induced traumatic brain injury via regulation of JNK/P38 MAPK signaling pathway.

European journal of pharmacology·2026

Structure-Optimized Asymmetric siRNA Increases Predicted AGO2 Binding Affinity to Augment Targeted MMP7 Gene Silencing Efficacy.

European journal of pharmacology·2026

The dynamic nature of mineral organic matter associations in adsorption experiments.

Chemosphere·2026

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Langmuir : the ACS journal of surfaces and colloids·2026

Unveiling Mechanisms of Chlorinated Volatile Organic Compounds (CVOCs) and 1,4-Dioxane Sorption in Macrocyclic Materials: A DFT, MD, and Experimental Study.

Langmuir : the ACS journal of surfaces and colloids·2026

Monte Carlo Simulation of Cooperative Condensation in Nanopore Networks.

Langmuir : the ACS journal of surfaces and colloids·2026

Sub-20 nm Hard X-ray Spectromicroscopy Reveals Nanoscale Redox Heterogeneity in Ultrafine Particulates.

ACS nano·2026

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ACS macro letters·2026

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Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency.

Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies.

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