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Related Experiment Videos

Anemia producing mitral valve flutter on the echocardiogram.

K H Tye, K B Desser, A Benchimol

    Angiology
    |May 1, 1979
    PubMed
    Summary

    Anemia can cause abnormal mitral valve fluttering, a finding often mistaken for aortic insufficiency. This study suggests increased blood flow due to anemia is the likely cause, particularly in patients with chronic kidney disease.

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    Area of Science:

    • Cardiology
    • Nephrology
    • Hematology

    Background:

    • Diastolic mitral valve fluttering is a rare echocardiographic finding.
    • Its association with anemia, particularly in chronic renal failure (CRF) and uterine bleeding, is not well-established.
    • Distinguishing this fluttering from aortic insufficiency murmurs is clinically important.

    Purpose of the Study:

    • To investigate the prevalence of diastolic mitral valve fluttering in patients with anemia.
    • To explore the potential link between anemia and diastolic mitral valve fluttering.
    • To differentiate this finding from aortic regurgitation in anemic patients.

    Main Methods:

    • Echocardiography was performed on 34 patients with anemia due to CRF and one with uterine bleeding.
    • Patients were in sinus rhythm.
    • Clinical assessment for aortic insufficiency was also conducted.

    Main Results:

    • Eighteen percent (6/34) of anemic patients exhibited major diastolic mitral valve fluttering.
    • An additional 4 patients had equivocal fluttering.
    • No subjects showed clinical signs of aortic insufficiency; mitral valve motion normalized post-transfusion in the uterine bleeding patient.

    Conclusions:

    • Anemia, likely due to increased blood flow, can induce diastolic mitral valve fluttering.
    • This finding may be misinterpreted as aortic regurgitation, especially in uremic patients.
    • Clinical caution is advised when evaluating diastolic murmurs in anemic individuals.

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