Related Experiment Videos
Choroid plexus papilloma and infantile spasms.
Annals of Neurology
|March 1, 1979
Summary
Infantile spasms in an infant resolved after treatment with corticotropin and surgical removal of a choroid plexus papilloma. The infant experienced significant clinical and electroencephalographic improvements, leading to full recovery.
Area of Science:
- Pediatric Neurology
- Neuro-oncology
Background:
- Infantile spasms syndrome (ISS) is a severe epilepsy syndrome in infants.
- Hypsarrhythmia on electroencephalography (EEG) is a characteristic finding.
- Choroid plexus papillomas are rare tumors that can cause neurological symptoms.
Purpose of the Study:
- To report a case of infantile spasms associated with a choroid plexus papilloma.
- To describe the treatment and outcome in this unique case.
Main Methods:
- A 7-month-old infant diagnosed with infantile spasms syndrome was treated with corticotropin.
- EEG monitoring was performed to assess neurological abnormalities.
- Surgical resection of a left lateral ventricle choroid plexus papilloma was performed.
Main Results:
- Corticotropin treatment led to improvement in clinical symptoms and EEG abnormalities.
- Surgical removal of the choroid plexus papilloma resulted in complete clinical recovery.
- The infant was seizure-free, developmentally and neurologically normal one year post-surgery.
Conclusions:
- Choroid plexus papilloma can be a treatable cause of infantile spasms syndrome.
- A combination of medical and surgical treatment can lead to excellent outcomes.
- Early diagnosis and intervention are crucial for managing complex pediatric neurological conditions.