Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dermatomyositis and toxoplasmosis.

G F Hendrickx, J Verhage, F G Jennekens

    Annals of Neurology
    |April 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Risk factors and monitoring for water quality to determine best management practices for splash parks.

    Journal of water and health·2014
    Same author

    Health risk assessment for splash parks that use rainwater as source water.

    Water research·2014
    Same author

    Human exposure to endotoxins and fecal indicators originating from water features.

    Water research·2013
    Same author

    Quantitative assessment of infection risk from exposure to waterborne pathogens in urban floodwater.

    Water research·2013
    Same author

    Immunohistochemical detection of brain tissue in heated meat products.

    Meat science·2011
    Same author

    Report 1977-1978 concerning Trichinella spiralis studies in the Netherlands.

    The veterinary quarterly·2011

    Childhood dermatomyositis may be caused by toxoplasmosis. Active toxoplasmosis was found in a patient with dermatomyositis, and symptoms improved with treatment.

    Area of Science:

    • Immunology
    • Infectious Diseases
    • Pediatric Rheumatology

    Background:

    • Childhood dermatomyositis is a rare autoimmune disease affecting muscles and skin.
    • The etiology of childhood dermatomyositis remains largely unknown.
    • Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii.

    Purpose of the Study:

    • To investigate a potential link between toxoplasmosis and childhood dermatomyositis.
    • To present a case study of a patient with both conditions.

    Main Methods:

    • Serological testing for toxoplasma antibodies.
    • Direct immunofluorescence of muscle biopsy.
    • Clinical assessment of patient response to treatment.

    Main Results:

    Related Experiment Videos

    • The patient presented with high toxoplasma antibodies at diagnosis.
    • Active toxoplasmosis was confirmed in the muscle biopsy.
    • The patient showed improvement following treatment.

    Conclusions:

    • Toxoplasmosis is a potential, previously unrecognized cause of childhood dermatomyositis.
    • Further research is warranted to explore this association in a larger cohort.