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Pseudomembranous enterocolitis in adults.

T Coutsoftides, S P Benjamin, V W Fazio

    Annals of Surgery
    |April 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Pseudomembranous enterocolitis, often triggered by surgery or illness, presents with fever, diarrhea, and abdominal pain. Early diagnosis is crucial as treatment success rates remain low.

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    Area of Science:

    • Gastroenterology
    • Colorectal Surgery
    • Infectious Diseases

    Background:

    • Pseudomembranous enterocolitis is a severe intestinal condition.
    • It is frequently associated with prior surgical procedures or significant medical comorbidities.
    • Understanding its clinical presentation and diagnostic challenges is vital.

    Purpose of the Study:

    • To review cases of pseudomembranous enterocolitis over a 17-year period.
    • To identify common inciting factors, symptoms, and affected organs.
    • To evaluate diagnostic accuracy and treatment outcomes.

    Main Methods:

    • Retrospective case series analysis.
    • Review of clinical records for 21 patients diagnosed with pseudomembranous enterocolitis.
    • Analysis of patient history, symptoms, diagnostic findings, and treatment responses.

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    Main Results:

    • Twenty-one patients were identified over 17 years.
    • Common triggers included antecedent operations and serious medical illnesses.
    • Fever, diarrhea, and abdominal pain were the most frequent symptoms; the colon was most commonly involved.
    • Diagnosis was frequently missed, and neither conservative nor surgical treatments were successful.

    Conclusions:

    • Pseudomembranous enterocolitis requires heightened clinical awareness for timely diagnosis.
    • Improved diagnostic strategies are needed to increase cure rates.
    • Further research into effective therapeutic interventions is warranted.