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Peripheral lymphadenopathy in Nigeria.

E B Attah

    Tropical and Geographical Medicine
    |September 1, 1974
    PubMed
    Summary

    Peripheral lymph node biopsies reveal tuberculosis, Hodgkin's disease, and metastatic tumors as common causes of persistent lymphadenopathy. Diagnosis and frequency vary by biopsy site, with cervical nodes most affected.

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    Area of Science:

    • Pathology
    • Oncology
    • Infectious Diseases

    Background:

    • Peripheral lymphadenopathy is a common clinical sign requiring diagnostic evaluation.
    • Understanding the etiological spectrum of lymphadenopathy is crucial for timely diagnosis and management.

    Purpose of the Study:

    • To analyze the spectrum of diseases presenting as peripheral lymphadenopathy.
    • To determine the clinical correlates and common causes of lymphadenopathy in Ibadan.

    Main Methods:

    • Retrospective analysis of 176 peripheral lymph node biopsies.
    • Review of histopathological findings and clinical data.

    Main Results:

    • Tuberculosis, Hodgkin's disease, and secondary tumors were the most frequent diagnoses.
    • Metastatic tumors were more common in patients over 20 years old.
    • Nonspecific reactive alterations constituted the largest group of findings; cervical lymph nodes were most frequently biopsied.

    Conclusions:

    • Tuberculosis and Hodgkin's disease are likely diagnoses in generalized lymphadenopathy.
    • The diagnostic yield of lymphadenopathy varies with biopsy site.
    • Peripheral lymph node biopsy remains essential for diagnosing various conditions presenting with lymphadenopathy.

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