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[Coumarin-induced fetal abnormalities and stippled epiphyses]
Archives Francaises De Pediatrie
|January 1, 1979
Summary
Most anticoagulants can cross the placenta, risking fetal hemorrhage. Warfarin sodium, specifically, is linked to teratogenic effects, as illustrated by this newborn case report.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Pharmacology
Background:
- Anticoagulants, excluding heparin, are known to cross the placenta.
- Placental transfer of anticoagulants can lead to fetal hemorrhage.
- The teratogenic effects of warfarin sodium are a documented concern.