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Related Experiment Videos

Appendicitis in acute leukemia.

K Ver Steeg, A LaSalle, I Ratner

    Archives of Surgery (Chicago, Ill. : 1960)
    |May 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Appendicitis in children with acute leukemia requires surgical management. Appendectomy is a safe procedure, with one case showing spontaneous remission, but relapsed patients face complications.

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    Area of Science:

    • Pediatric Oncology
    • Surgical Gastroenterology

    Background:

    • Appendicitis is a rare complication in children with acute leukemia.
    • Patients with acute leukemia may present atypical appendicitis symptoms, especially when on prednisone therapy.

    Purpose of the Study:

    • To review the clinical presentation, management, and outcomes of appendicitis in pediatric patients with acute leukemia.
    • To evaluate the safety and efficacy of surgical intervention for appendicitis in this patient population.

    Main Methods:

    • Retrospective case review of five pediatric patients diagnosed with acute leukemia and complicated by appendicitis.
    • Analysis of clinical signs, symptoms, treatment (appendectomy), and postoperative outcomes.

    Main Results:

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  • All five patients underwent appendectomy and survived the immediate postoperative period.
  • Four patients were receiving prednisone, yet presented with typical appendicitis symptoms.
  • One patient achieved spontaneous remission post-appendectomy; two of three relapsed patients experienced severe postoperative complications.

    • Conclusions:

    • Surgical management, specifically appendectomy, is supported for appendicitis in children with acute leukemia.
    • While generally safe, careful monitoring is crucial, particularly for patients in relapse, due to potential severe postoperative complications.