Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current required for ventricular defibrillation.

J N Patton, J F Pantridge

    British Medical Journal
    |February 24, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Ventricular defibrillation requires significantly less current than predicted from animal studies. Current needs do not correlate with body weight, suggesting lower energy defibrillators may suffice.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Giant follicular lymphoblastoma (Brill-Symmers' disease).

    The Ulster medical journal·2010
    Same author

    Beriberi; etiological and clinical considerations.

    The Ulster medical journal·2010
    Same author

    Aggressive secondary prevention: a perspective from the coronary interventional setting.

    Journal of interventional cardiology·2002
    Same author

    Concomitant laparoscopic cholecystectomy and splenectomy for surgical management of hereditary spherocytosis.

    The American surgeon·1997
    Same author

    The revolution and evolution of prehospital cardiac care.

    Archives of internal medicine·1996
    Same author

    A history of prehospital coronary care.

    The Ulster medical journal·1996
    Same journal

    Muscular pain during therapy with carbenoxolone (Biogastrone).

    British medical journal·2016
    Same journal

    ACUTE INTESTINAL OBSTRUCTION DUE TO INTRA-ABDOMINAL CAUSES.

    British medical journal·2014
    Same journal

    A CASE OF HAEMATIDROSIS.

    British medical journal·2014
    Same journal

    Incidence of ulcer in haematemesis.

    British medical journal·2011
    Same journal

    Pituitary hypothyroidism with impaired renal function.

    British medical journal·2011
    Same journal

    The fenestration operation for otosclerosis.

    British medical journal·2011
    See all related articles

    Area of Science:

    • Cardiology
    • Medical Devices
    • Electrophysiology

    Background:

    • Ventricular defibrillation is critical for treating cardiac arrest.
    • Estimates of required electrical current have largely relied on animal models.
    • Optimizing defibrillator energy storage is crucial for device design and patient safety.

    Purpose of the Study:

    • To determine the actual mean current required for effective ventricular defibrillation in humans.
    • To compare human defibrillation current requirements with predictions from animal experiments.
    • To assess the relationship between body weight and defibrillation current needs.

    Main Methods:

    • Measurement of the mean current necessary for ventricular defibrillation.
    • Statistical analysis to determine correlation between current and body weight.

    Related Experiment Videos

  • Evaluation of energy storage requirements based on measured current.

    • Main Results:

    • The mean current required was 0.35 +/- 0.03 A/kg body weight.
    • This value is approximately one-third of that predicted from animal experiments.
    • No significant correlation was found between the current required and body weight (r = -0.007 +/- 0.213).

    Conclusions:

    • Human ventricular defibrillation requires less current than previously estimated from animal data.
    • Defibrillator energy storage up to 400 Joules appears sufficient, challenging the need for higher capacity devices.
    • These findings have implications for the design and calibration of automated external defibrillators (AEDs) and implantable cardioverter-defibrillators (ICDs).