Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Severe hypernatraemia in adults.

P Daggett, J Deanfield, F Moss

    British Medical Journal
    |May 5, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Severe hypernatraemia in adults is uncommon. This study found it linked to diabetes mellitus, intracranial disorders, and dehydration, often exacerbated by specific saline treatments.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Erratum: Centrality-Dependent Modification of Jet-Production Rates in Deuteron-Gold Collisions at sqrt[s_{NN}]=200  GeV [Phys. Rev. Lett. 116, 122301 (2016)].

    Physical review letters·2025
    Same author

    Geographical Variation in Underlying Social Deprivation, Cardiovascular and Other Comorbidities in Patients with Potentially Curable Cancers in England: Results from a National Registry Dataset Analysis.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2023
    Same author

    Measurement of Direct-Photon Cross Section and Double-Helicity Asymmetry at sqrt[s]=510  GeV in p[over →]+p[over →] Collisions.

    Physical review letters·2023
    Same author

    Probing Gluon Spin-Momentum Correlations in Transversely Polarized Protons through Midrapidity Isolated Direct Photons in p^{↑}+p Collisions at sqrt[s]=200  GeV.

    Physical review letters·2021
    Same author

    Nuclear Dependence of the Transverse Single-Spin Asymmetry in the Production of Charged Hadrons at Forward Rapidity in Polarized p+p, p+Al, and p+Au Collisions at sqrt[s_{NN}]=200  GeV.

    Physical review letters·2019
    Same author

    Understanding the Fertilizer Management Impacts on Water and Nitrogen Dynamics for a Corn Silage Tile-Drained System in Canada.

    Journal of environmental quality·2019
    Same journal

    Muscular pain during therapy with carbenoxolone (Biogastrone).

    British medical journal·2016
    Same journal

    ACUTE INTESTINAL OBSTRUCTION DUE TO INTRA-ABDOMINAL CAUSES.

    British medical journal·2014
    Same journal

    A CASE OF HAEMATIDROSIS.

    British medical journal·2014
    Same journal

    Incidence of ulcer in haematemesis.

    British medical journal·2011
    Same journal

    Pituitary hypothyroidism with impaired renal function.

    British medical journal·2011
    Same journal

    The fenestration operation for otosclerosis.

    British medical journal·2011
    See all related articles

    Area of Science:

    • Nephrology
    • Endocrinology
    • Neurology

    Background:

    • Abnormalities in plasma sodium concentration, particularly hypernatraemia, are critical clinical issues.
    • Understanding the causes and management of severe hypernatraemia is essential for patient outcomes.

    Purpose of the Study:

    • To investigate the causes and clinical characteristics of severe hypernatraemia (plasma sodium > 154 mmol/l) in adult patients.
    • To analyze the role of underlying conditions and treatments in the development of hypernatraemia.

    Main Methods:

    • Prospective study over one year identifying 20 patients with severe hypernatraemia.
    • Analysis of patient groups: diabetes mellitus, primary intracranial disorder, and dehydration.
    • Correlation analysis between plasma sodium and blood glucose changes in diabetic patients.

    Related Experiment Videos

    Main Results:

    • Hypernatraemia developed in 8 diabetic patients despite hypotonic saline treatment, correlating with blood glucose changes.
    • 8 patients with intracranial disorders showed abnormal antidiuretic hormone production, with high mortality in this group.
    • 4 dehydrated patients, two with gastrointestinal hemorrhage, developed hypernatraemia partly due to 0.9% saline infusion.

    Conclusions:

    • Severe hypernatraemia in adults has diverse causes including diabetes, intracranial issues, and dehydration.
    • Treatment strategies, especially saline administration, can inadvertently worsen hypernatraemia in certain conditions.
    • Frequent biochemical monitoring and intensive care unit management are crucial for severe hypernatraemia cases.