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An improved program to calculate intrapulmonary shunting.

D Siegel, S Ramanathan, J Chalon

    Critical Care Medicine
    |June 1, 1979
    PubMed
    Summary
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    A computer program was created to calculate intrapulmonary venous admixture using a programmable calculator. This tool accounts for temperature, pH, and CO2 variations, improving accuracy in blood oxygen calculations.

    Area of Science:

    • Physiology
    • Computer Science
    • Medical Instrumentation

    Background:

    • Accurate calculation of intrapulmonary venous admixture is crucial for assessing respiratory function.
    • Existing methods may lack comprehensive corrections for physiological variables.
    • Programmable calculators offer a portable solution for complex physiological calculations.

    Purpose of the Study:

    • To develop a computer program for calculating intrapulmonary venous admixture.
    • To implement corrections for physiological variables affecting blood oxygenation.
    • To adapt the calculation for a Texas Instruments TI 59 programmable calculator.

    Main Methods:

    • Developed a program for the TI 59 programmable calculator.
    • Incorporated a correction for saturated water vapor pressure varying with body temperature.

    Related Experiment Videos

  • Modeled the standard oxyhemoglobin dissociation curve and included correction factors for pH and CO2 tension shifts.
  • Corrected oxygen tensions from electrode to patient temperature and calculated variations in the Bunsen solubility coefficient of oxygen.

    • Main Results:

    • A functional computer program was developed for calculating intrapulmonary venous admixture.
    • The program integrates multiple physiological corrections for enhanced accuracy.
    • The calculation is feasible on a TI 59 programmable calculator.

    Conclusions:

    • The developed program provides a method for calculating intrapulmonary venous admixture with incorporated physiological corrections.
    • This approach enhances the accuracy of venous admixture calculations in clinical or research settings.
    • Programmable calculators can be effectively utilized for complex physiological computations.