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Pathogenicity of ureaplasmas for animals and man
Zentralblatt Fur Bakteriologie, Parasitenkunde, Infektionskrankheiten Und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie Und Parasitologie
|October 1, 1979
Summary
Ureaplasmas, previously T-strain mycoplasmas, are linked to various animal and human diseases. While evidence suggests they cause non-gonococcal urethritis in some men, their role in infertility and abortion remains unclear.
Area of Science:
- Microbiology
- Veterinary Medicine
- Human Infectious Diseases
Background:
- Ureaplasmas, formerly T-strain mycoplasmas, are found in the genital tracts of humans and various animal species.
- Experimental studies indicate ureaplasmas can cause mastitis in cattle, goats, and mice, and may contribute to bovine pneumonia.
Purpose of the Study:
- To review the current understanding of ureaplasma's role in animal and human diseases.
- To assess the evidence linking ureaplasmas to genitourinary diseases, infertility, and pregnancy complications.
Main Methods:
- Review of experimental studies and naturally occurring disease observations.
- Analysis of isolation data, inoculation experiments, and treatment outcomes.
Main Results:
- Ureaplasmas experimentally cause mastitis and are implicated in bovine pneumonia.
- Evidence suggests ureaplasmas cause non-gonococcal urethritis in some men.
- A clear causal link between ureaplasmas and naturally occurring genital tract disease, infertility, or abortion in humans is not established, though associations exist.
Conclusions:
- Ureaplasmas are significant pathogens in certain animal models and a suspected cause of non-gonococcal urethritis in humans.
- Further research is needed to clarify the role of ureaplasmas in human infertility and pregnancy outcomes.
- The association with chorioamnionitis warrants further investigation.