Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mucor mediastinitis.

B A Connor, R J Anderson, J W Smith

    Chest
    |April 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    A rare case of mucormycosis infection in a leukemia patient led to widespread organ invasion. This fungal infection proved fatal, affecting the heart, arteries, and spinal cord.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reiter syndrome following protracted symptoms of Cyclospora infection.

    Emerging infectious diseases·2001
    Same author

    Achieving immunization in adults: opportunities presented by travel clinics in the US.

    Journal of travel medicine·2001
    Same author

    Randomized, double-blind study in healthy adults to assess the boosting effect of Vaqta or Havrix after a single dose of Havrix.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2001
    Same author

    Omeprazole or ranitidine bismuth citrate triple therapy to treat Helicobacter pylori infection: a randomized, controlled trial in Vietnamese patients with duodenal ulcer.

    Alimentary pharmacology & therapeutics·2000
    Same author

    Pulmonary edema in malaria.

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·1999
    Same author

    Chronic diarrhea in the returned traveler.

    The Medical clinics of North America·1999
    Same journal

    Wearable-derived activity and physiological changes following pleural intervention in malignant pleural effusion.

    Chest·2026
    Same journal

    The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

    Chest·2026
    Same journal

    A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

    Chest·2026
    Same journal

    Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

    Chest·2026
    Same journal

    Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

    Chest·2026
    Same journal

    Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

    Chest·2026
    See all related articles

    Area of Science:

    • Medical Mycology
    • Hematology
    • Cardiovascular Pathology

    Background:

    • Lymphocytic leukemia is a hematologic malignancy that can compromise immune function.
    • Patients with hematologic malignancies are at increased risk for opportunistic infections.
    • Mucormycosis is a rare but aggressive fungal infection, often fatal in immunocompromised individuals.

    Observation:

    • A 69-year-old male with lymphocytic leukemia presented with systemic symptoms including fever and a pericardial friction rub.
    • Clinical course was complicated by atrial fibrillation, refractory hypotension, and acute paraplegia.
    • Radiological findings included widening of the mediastinum and left pleural effusion.

    Findings:

    • Post-mortem examination revealed extensive invasion by mucormycosis.

    Related Experiment Videos

  • The infection had infiltrated the mediastinum, myocardium, mediastinal and coronary arteries, and spinal arteries.
  • This widespread dissemination highlights the aggressive nature of mucormycosis in immunocompromised hosts.

    • Implications:

    • This case underscores the critical importance of early recognition and management of invasive fungal infections in leukemia patients.
    • Aggressive mucormycosis can lead to rapid multi-organ failure and death.
    • Further research into diagnostic and therapeutic strategies for mucormycosis in immunocompromised populations is warranted.