[Change in the antinociceptive effect occurring in stimulation of the rat midbrain under the influence of morphine]
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Farmakologiia I Toksikologiia
|May 1, 1979
Abstract:
In chronic experiments on rats it was established that electric stimulation of certain areas of the midbrain depresses pain reactions of different genesis. Morphine in subanalgetic doses (2--2.5 mg/kg) reveals and potentiates the antinociceptive effect of central stimulation shown first of all by depression of the complex highly integrated components of an emotionally behavioral conductive reaction to pain.