[The effect of biguanide preparations on lipid metabolism]

The effect of biguanide preparations Silubin retard and Dibotin on cholesterin serum level and total fats was experimentally and clinically checked. The experimental investigations were carried out on rabbits with and without corticosteroid diabetes and the clinical--on 142 patients with diabetes. The bigguanide preparations was concluded to reduce both total fats and cholesterin. The higher the initial values of the mentioned indices, the more manifested their effect.