Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changing time perception with antidepressant drug therapy.

E Edelstein

    Psychiatria Clinica
    |January 1, 1974
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Integrated structure-based protein interface prediction.

    BMC bioinformatics·2022
    Same author

    Luteinized thecoma associated with sclerosing peritonitis--conservative surgical approach followed by corticosteroid and GnRH agonist treatment--a case report.

    Gynecologic oncology·2008
    Same author

    Primary peritoneal borderline tumor. A case report and review of the literature.

    European journal of gynaecological oncology·2003
    Same author

    Synchronous mucinous tumors of the ovary and the appendix associated with pseudomyxoma peritonei: CT findings.

    Abdominal imaging·2000
    Same author

    Adenocarcinoma arising from the gastrointestinal epithelium in benign cystic teratoma of the ovary.

    Gynecologic oncology·1998
    Same author

    Epidemic Bacillus endophthalmitis after cataract surgery I: acute presentation and outcome.

    Ophthalmology·1997

    Depressed patients often misjudge time, typically overestimating short durations. Antidepressant treatment improved this time sense, though morning estimations remained less accurate.

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Chronobiology

    Background:

    • Depression is associated with altered cognitive functions.
    • Time perception deficits may be a symptom of depression.
    • Tricyclic antidepressants are a common treatment for depression.

    Purpose of the Study:

    • To investigate the time sense in patients with depression.
    • To evaluate the effect of tricyclic antidepressant therapy on time estimation.
    • To explore diurnal variations in time perception during treatment.

    Main Methods:

    • Pilot study involving ten depressed patients.
    • Time estimation tasks measuring short time spans using two different methods.
    • Measurements conducted in both morning and evening hours.

    Related Experiment Videos

  • Assessment before, during, and after tricyclic antidepressant therapy.

    • Main Results:

    • Time estimation accuracy was significantly deviant in depressed patients.
    • Most patients (all but one) overestimated short time intervals.
    • Improvement in depressive symptoms correlated with enhanced time sense.
    • Time estimation errors were consistently greater in the morning compared to the evening.

    Conclusions:

    • Time perception deficits are notable in depression and may improve with treatment.
    • Tricyclic antidepressants appear to positively influence time sense.
    • Diurnal variations in time estimation persist even with treatment, suggesting underlying mechanisms.