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[Pneumococcal capsular types of clinical specimens. Lyon: 1972-1977 and 1978 (author's transl)]
Abstract:
878 strains of Streptococcus pneumoniae were tested during two periods : 667 strains from 1972 to 1977 and 211 strains during 1978. Strains were isolated from spinal fluids, blood, peritoneal fluids, urines, exudate from respiratory tract except sputum. In polymicrobial specimens, only the predominant species were serotyped. From 1972 to 1977, 53,3% of strains are typed and 6 serotypes and pools are prevalent among 68,5% of typed strains, the most frequent are : 6 - D - 18 - 19. During the second period (1978) 82,5% of strains are typed, 9 serotypes are prevalent among 68,5% of typed strains, the most frequent are : 6 - 19 - 23 - 3. During 1978, 27,6% of strains are isolated from child wards, others from adults wards. A comparison of the relative frequencies of the serotypes in the two wards shows that the following 10 serotypes are the most frequent: 6 - 19 - 23 - 3 - 18 - 1 - 8 - 9 - 14 - 4.
Insights
Streptococcus pneumoniae serotype prevalence shifted between 1972-1977 and 1978, with distinct serotypes dominating in adult and pediatric wards. This highlights evolving pneumococcal epidemiology.
Area of Science:
- Microbiology
- Epidemiology
- Public Health
Context:
- Analysis of 878 Streptococcus pneumoniae strains isolated from various clinical specimens between 1972-1978.
- Focus on serotyping to understand the distribution and prevalence of different pneumococcal serotypes.
- Inclusion of strains from both early (1972-1977) and later (1978) periods to track epidemiological changes.
Purpose:
- To determine the prevalent serotypes of Streptococcus pneumoniae over two distinct time periods.
- To compare serotype frequencies between adult and pediatric wards during 1978.
- To identify shifts in pneumococcal serotype distribution and their potential public health implications.
Summary:
- During 1972-1977, serotypes 6, D, 18, and 19 were most common, with 53.3% of strains typed.
- In 1978, typing increased to 82.5%, with serotypes 6, 19, 23, and 3 becoming most frequent.
- Serotype distribution varied between adult and pediatric wards in 1978, with serotypes 6, 19, 23, and 3 being most prevalent overall.
Impact:
- Provides crucial data on the changing epidemiology of Streptococcus pneumoniae, essential for vaccine development and public health strategies.
- Highlights the importance of ongoing surveillance of pneumococcal serotypes to inform effective disease prevention and control measures.
- Demonstrates serotype-specific differences in isolation from pediatric versus adult populations, aiding targeted interventions.