Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Role of visual cortex in interocular alignment.

M Cynader

    Investigative Ophthalmology & Visual Science
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    The visual cortex is crucial for proper eye alignment in cats. Removing it in young kittens leads to abnormal eye torsion, highlighting its role in visual development.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Isoform-specific palmitoylation of JNK regulates axonal development.

    Cell death and differentiation·2011
    Same author

    Perspectives: neuroscience. Strengthening visual connections.

    Science (New York, N.Y.)·2001
    Same author

    Introductory comments on neuroprotection.

    Survey of ophthalmology·1999
    Same author

    A perspective of gene therapy in the glaucomas.

    Survey of ophthalmology·1999
    Same author

    Immunohistochemical localization of dopamine-beta-hydroxylase in human and monkey eyes.

    Current eye research·1999
    Same author

    Comparison of the neuroprotective effects of APV and bcl-2 in glutamate-induced cell death.

    Neuroreport·1997
    Same journal

    Impact of Subretinal Drusenoid Deposits on Ellipsoid Zone-Related Thickness Metrics.

    Investigative ophthalmology & visual science·2026
    Same journal

    Proteomic Profiling of Optic Nerves From SMOX-Deficient Mice Identifies Regulators of Neuroinflammation and Axonal Damage in Optic Neuritis.

    Investigative ophthalmology & visual science·2026
    Same journal

    Aflibercept and Faricimab Equipotently Restore Endothelial Barrier Function.

    Investigative ophthalmology & visual science·2026
    Same journal

    Spatial Decomposition of Longitudinal RNFL Maps Reveals Distinct Modes of Glaucomatous Progression With Structure-Function and Genetic Signatures.

    Investigative ophthalmology & visual science·2026
    Same journal

    The CXXC1-IGFBP6 Axis Maintains Corneal Epithelial Differentiation via H3K4me3-Dependent Transcriptional Activation.

    Investigative ophthalmology & visual science·2026
    Same journal

    Archetypal Visual Field Analysis of Patients With Chronic Leber Hereditary Optic Neuropathy in Relation to Visual Recovery.

    Investigative ophthalmology & visual science·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Developmental Biology

    Background:

    • Interocular alignment is essential for binocular vision.
    • The visual cortex's role in eye alignment development is not fully understood.

    Purpose of the Study:

    • To investigate the visual cortex's role in the development of interocular alignment in cats.
    • To determine the effects of visual cortex removal at different developmental stages and under varying visual conditions.

    Main Methods:

    • Bilateral removal of the visual cortex in kittens and adult cats.
    • Suturing eyelids to prevent binocular vision.
    • Dark-rearing followed by light exposure.
    • Observation of eye alignment (incyclotorsion, excyclotorsion, strabismus).

    Related Experiment Videos

    Main Results:

    • Neonatal visual cortex lesions in kittens led to normal alignment initially, followed by incyclotorsion around 60-80 days.
    • Preventing binocular vision in lesioned kittens frequently caused strabismus and incyclotorsion.
    • Adult cats with visual cortex lesions showed no significant eye alignment changes.
    • Dark-reared cats exhibited incyclotorsion upon light exposure, which was largely prevented by decortication.

    Conclusions:

    • The visual cortex plays a critical role in the development of torsional eye alignment.
    • Early-life visual cortex function is essential for maintaining normal eye alignment.
    • Visual experience and cortical development are interdependent for proper ocular motor control.