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Structural changes in aging human skin.

W Montagna, K Carlisle

The Journal of Investigative Dermatology

|July 1, 1979

Summary

This summary is machine-generated.

Skin aging causes epidermal flattening and reduced blood vessels. While sun exposure worsens these changes, aging also affects sensory organs, especially in the genitalia, leading to their reduction or disappearance.

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Area of Science:

Dermatology
Gerontology
Anatomy

Background:

Skin aging leads to epidermal thinning and reduced vascularity.
Sun exposure exacerbates age-related skin changes.
Elastic fiber framework in the papillary dermis is crucial for skin structure.

Purpose of the Study:

To review the architecture of the elastic fiber framework in protected skin.
To compare aging changes in sun-protected versus sun-exposed skin.
To investigate the effect of aging on cutaneous sensory end organs.

Main Methods:

Review of existing literature on skin aging.
Histological examination of skin samples (implied).
Comparative analysis of aged skin from different exposure areas.

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Main Results:

Epidermal flattening and rarefaction of superficial blood vessels occur with age in both exposed and protected skin.
Aging changes in sun-protected skin are similar but less severe than in sun-exposed skin.
Most cutaneous sensory end organs are unaffected by aging, except those in the external genitalia.

Conclusions:

Skin aging involves structural changes in the epidermis and vasculature.
Sun exposure significantly accelerates skin aging.
Specific sensory nerve endings in the female genitalia are particularly vulnerable to age-related degeneration.